Consequences of fetomaternal haemorrhage after intrauterine transfusion.

Consequences of fetomaternal haemorrhage after intrauterine transfusion.

Fetomaternal haemorrhage was studied after 68 consecutive fetal intravascular transfusions performed in 20 patients with Rh isoimmunisation. alpha Fetoprotein concentration was assayed in maternal blood taken before, and immediately after each transfusion and three and 24 hours later. An increase of 50% or more in the concentration in any of the samples after transfusion was considered to indic...

[Intrauterine transfusion].

Survival of donor cells 25 years after intrauterine transfusion.

Persistence of donor leukocytes in the circulation of recipients of intrauterine transfusion (IUT) has been observed up to 5 years after birth. The aim of this study was to determine whether transfusions with nonirradiated, nonleukocyte-depleted donor blood during the fetal period resulted in long-term immunomodulation of the recipient. Twenty-four surviving IUT recipients between 1966 and 1976...

Detection of fetomaternal haemorrhage by an immunofluorescence technique.

An inexpensive and simple technique for assessing fetomaternal bleeds in cases of Rh(D) incompatibility is described. The method is unlikely to replace the acid elution technique, but it may be of use in cases where results are in doubt owing to the presence of F cells of maternal origin.

Developmental outcome after intravascular intrauterine transfusion for rhesus haemolytic disease.

The development outcome of 16 infants who had rhesus disease was assessed at 18 months. Eight had received intravascular intrauterine transfusion and eight postnatal exchange transfusions. There was no difference in developmental outcome and neither group was different from the population as a whole.